Generic Alfacip (Alfacalcidol)
Alfacip
Alfacip is used to treat osteoporosis and conditions with impairments of calcium metabolism such as bone loss due to age.
Package
Price
Per Pills
Savings
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0.25 mg x 30 pills
$80.99
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0.25 mg x 240 pills
$383.99
$1.60
$264.00
Package
Price
Per Pills
Savings
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0.5 mcg x 30 pills
$238.99
$7.97
$0.00
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$397.99
$6.63
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$1 224.99
$5.10
$688.80
Product Description
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Common use

Alfacip (an analogue of vitamin D) contains active ingredient Alfacalcidol and administered to treat conditions with impairments of calcium metabolism caused by 1-О± hydroxylation disorders such as when there is reduced renal function. The conditions treated by Alfacip are renal osteodystrophy, hyperparathyroidism (a disorder with parathyroid hormone deficiency, the substance required for the absorption of calcium and phosphorus), hypoparathyroidism, neonatal hypocalcaemia, nutritional and malabsorptive rickets and osteomalacia, pseudo-deficiency (D-dependent) rickets and osteomalacia, hypophosphataemic vitamin D resistant rickets and osteomalacia, osteoporosis.



Dosage and direction

Daily dose of Alfacip is 1 mcg/day. The dose should be reduced in the elderly, neonates and premature infants, children under 20 kg bodyweight.



Precautions

The patients treated by Alfacip should be regularly tested to avoid hypercalcaemia for plasma levels of calcium, parathyroid hormone, alkaline phosphatase, radiographic and histological investigations. The tests are needed especially for the patients with chronic renal failure because the decline of renal function may be aggravated by prolonged hypercalcaemia.



Contraindications

Patients with hypercalcaemia, metastatic calcification, hyperphosphataemia (except when occurring with hypoparathyroidism) or hypermagnesaemia, vitamin D toxicity or hypersensitivity to the vitamin D or its analogues cannot be treated by Alfacip.



Possible side effect

The following adverse reactions may occur: hypercalcemia, malaise, tiredness, weakness, nausea and vomiting, headache and dizziness, constipation or diarrhea, dry mouth, abdominal or gastrointestinal pain such as heartburn, heart palpitations, bone, muscle and joint pain.



Drug interaction

Long-term treatment with anticonvulsants, including phenytoin, may change vitamin D and calcium metabolism. This results in metabolic bone disease and hypocalcaemia and even seizures. Monitoring of calcium levels in the patients on antiepileptic drugs is required.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not increase your recommended dose. Take your doses at about the same time each day to avoid missing a dose.



Overdose

Signs of Alfacip overdose may be the following: high fever, high blood pressure, irregular heartbeat, stomach pain (severe).



Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets. Do not use after expiration term.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Doxycycline

Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.