Generic Cardarone (Amiodarone)
Cardarone is used in treatment of irregular heartbeat and to maintain a normal heart rate (ventricular fibrillation and ventricular tachycardia).
Per Pills
200 mg x 20 pills
200 mg x 30 pills
200 mg x 60 pills
200 mg x 90 pills
200 mg x 120 pills
Product Description
Abnormal liver enzyme results are common in patients on amiodarone. Ocular differential diagnosis 9th ed. Xenobiotic-sensing receptor modulators. If you have questions about side effects, call your doctor. All material copyright MediResource Inc. Draw up into a 30 mL syringe, then draw up 27 mL of D5W. Amiodarone is an antiarrhythmic medication used to treat and prevent a number of types of irregular heartbeats. The FDA was reluctant to officially approve the use of amiodarone since initial reports had shown increased incidence of serious pulmonary side-effects of the drug. The approved IV dosage recommended by the manufacturer for life-threatening ventricular arrhythmias for the first 24 hours is the following infusion regimen: initial IV rapid infusion of mg over the first 10 minutes. The authors recommended that dosing be based on body surface area in this age group rather than weight. Adult Critical Care Protocol:. Some of the other reported side effects of amiodarone therapy include neurologic problems fatigue, tremor, involuntary movements and poor coordinationgastrointestinal disturbances nausea, vomiting, constipation and anorexiaabnormalities involving the eye optic neuritis, optic neuropathy, blindness, photosensitivity and corneal and macular degenerationdermatological abnormalities photosensitivity and pigmentation changes and cardiovascular complications including congestive heart failure and decreased heart rate. Amiodarone mg-PAR, white, round. Because of the high iodine content of amiodarone, the thyroid gland is effectively saturated, thus preventing further uptake of isotopes of iodine. The relative efficacy of amiodarone and ICDs in preventing sudden Cardarone in patients without coronary Cardarrone is under investigation. Keep taking your medicine until your Cardagone tells you to stop. Oral: Take amiodarone exactly as prescribed by your doctor. However, recent studies have shown that aggressive attempts to maintain sinus rhythm using amiodarone or other drugs do not improve outcomes in relatively asymptomatic patients. Intravenously administered amiodarone is effective for the emergency treatment of ventricular tachyarrhythmias. Sources of funding: none reported. This information is very important for other medical treatments or surgeries you may have. The FDA categorizes medications based on safety for use during pregnancy. The time at which a previously controlled life-threatening arrhythmia will recur after discontinuation or dose adjustment is unpredictable, ranging from weeks to months. Choices for Care. Book Category Outline. Siddoway completed an internal medicine residency and clinical pharmacology and cardiology fellowships at Vanderbilt University Medical Center, Nashville. No specific maximum dosage guidelines are available. Food and Drug Administration FDA has labeled amiodarone only for the treatment of life-threatening ventricular arrhythmias, the drug also is used to treat atrial fibrillation. Indications Control of ventricular and supraventricular arrhythmias including those associated with Wolff-Parkinson-White syndrome. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. Chest radiograph; pulmonary function tests, Cardarone D lco. Heart J. Facts vs. Neonates and Infants. Amiodarone is categorized as a class III antiarrhythmic agentand prolongs phase 3 of the cardiac action potentialthe repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. Regardless, you should tell your doctor if you are pregnant or might become pregnant before taking this medication. A to Z List of Cancer Drugs. Handbook of Injectable Drugs 10th edition. Patients treated with amiodarone should be followed regularly to Cardarons ongoing need for amiodarone, efficacy of the drug, appropriateness of Cardaronne, adverse effects, and potential drug interactions. Anna K. Pilot agreement increases access to lab testing for paediatric oncology patients. The petitioner has identified no data or other information suggesting that CORDARONE amiodarone hydrochloride tablets, mg, were withdrawn for reasons of safety or effectiveness. About this Medication. Then, your dose may be decreased ranging from mg to mg per day. Some other serious side effects of amiodarone include:. The contents herein are for informational purposes only. These conditions often are dosage related and improve when the dosage is reduced. In the Advanced Cardiac Life Support ACLS guidelines published inamiodarone and procainamide are recommended for the initial treatment of hemodynamically stable wide-complex tachycardia. Warning This medicine is only used to treat abnormal heartbeats that may be deadly. Frederick National Laboratory for Cancer Research. History and physical examination directed at detecting anticipated adverse effects. Most individuals administered amiodarone on a chronic basis will experience at least one side effect. To select a suggestion, hit the enter key. Do not use with iodine allergy. Amiodarone mg-EON, yellow, round. Food and Drug Administration. If you Catdarone too many amiodarone, call your doctor or go to the nearest hospital right away. Are you sure? Subscribe to Drugs. There have been reports of fatal 'gasping syndrome' in neonates after the administration of IV solutions containing benzyl alcohol; symptoms include a striking onset of gasping respiration, hypotension, bradycardia, and cardiovascular collapse. Oral Liquid Formulations. Choose one. Do not Cadarone a double dose to Cardarlne up for a missed or skipped dose. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. This copyrighted material has been Cardarpne from a licensed data provider. Intravenously administered amiodarone causes heart block or bradycardia in 4. Siddoway completed an internal medicine residency and clinical pharmacology and cardiology fellowships at Vanderbilt University Medical Center, Nashville. These symptoms often are dosage related and usually improve when the dosage is reduced. Acne: Fact vs. Effectiveness of implantable defibrillators for preventing arrhythmic events and death: a meta-analysis. Choose a single article, issue, or full-access subscription. Amiodarone is a prescription medicine used in adults to treat life-threatening heartbeat problems called ventricular arrhythmias, for which other treatment did not work or was not tolerated. Always ask your health care professional for complete information about this product and your specific health needs. N Engl J Med. Sinus bradycardia. Monitor ECG and pulse oximetry continuously. The drug's high iodine content likely is a factor in its effects on the thyroid gland. Check for active clinical trials using this agent. Cardarone using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease lung disease thyroid problems This drug may make you dizzy. Amiodarone is a potent inhibitor of the hepatic and renal metabolism of several drugs Table 3. Digitoxin Digoxin Ouabain. The bioavailability of amiodarone is variable but generally poor, ranging from 22 to 95 percent. Drug Class. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Arch Intern Med. Amiodarone Bretylium Quinidine Verapamil. Ask your doctor or pharmacist for more information. Unusual Cancers of Childhood Treatment. Side Effects of Cancer Treatment. Call your doctor for medical advice about side effects. The President of the United States communicates information on holidays, commemorations, special observances, trade, and policy through Proclamations. Display Non-Printed Markup Elements. Defibrillation is the treatment of choice for ventricular fibrillation and pulseless ventricular tachycardia resulting in cardiac arrest. The major metabolite of amiodarone is desethylamiodarone DEAwhich is known to have antiarrhythmic properties. Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease lung disease thyroid problems This drug may make you dizzy. If you have any questions, consult your doctor or pharmacist. Retrieved Aug 22, Cordarone reviews. Amiodarone as compared with lidocaine for shock-resistant ventricular fibrillation [Published erratum appears in N Engl J Med ;]. Finding Health Care Services. Amiodarone inhibits peripheral conversion of thyroxine T4 to triiodothyronine T3 and may cause increased thyroxine concentrations, decreased T3 concentrations, and increased concentrations of inactive reverse T3 in euthyroid patients. If liver enzyme levels are three times higher than normal, amiodarone should be discontinued unless a patient is at high risk for recurrence of life-threatening arrhythmia. Enhanced Content - Document Print View.
Common use

The medication causes antiarrhythmic and antianginal effects. Antiarrhythmic effect is stipulated by diminishing of K+ ions transportation though cell membranes of myocites and diminishing of sinus node automaticity. Cardarone automatically blocks a- and b-adrenoreceptors. Relief of paroxysmal tachycardia attacks, relief of other heart attacks and treatment of ventricular fibrillation. Cardarone is for use only in life-threatening situations and should be used strictly according to recommendations of your doctor.

Dosage and direction

Cardarone may hurt stomach so it is recommended to take it with meals and in several daily doses to minimize damage.


Avoid drinking grapefruit juice, tanning and excessive UV irradiation, be careful doing work which requires high concentration of attention (driving and others).


Hypersensitivity to iodium or Cardarone. Sick sinus syndrome (sinus bradycardia, sinoatrial block) excluding cases of rythm correction with artificial pacemake. Disorders of atrioventricular or intra ventricular conduction (atrioventricular blocade of I-III degree), blocade of bundle Branch Block, disorders of thyroid gland, hypopotassiemia, pregnancy, breast-feeding, age below 18 years old, simultaneous treatment with MAO inhibitors.

Possible side effect

Lipofuscin deposit in cornea may cause appearance of shining spots or a 'fog' in front of eyes at bright light. Light pygmentation on open areas of skin, hypothyreosis, wheezing, cough, chest pain, trouble breathing, weight loss, thinning hair, feeling too hot or too cold, numbness, burning, pain, nausea, stomach pain. Call your doctor if you experience this or symptoms of allergy.

Drug interaction

Cardarone may interact with beta-blockers or certain calcium channel blockers leading to excessively slow heart rate or electrical impulse blockage in the heart. Blood levels of digoxin are increased at concurrent treatment with digoxin and Amiodarone. In case of treatment with digoxin its dose should be decreased by 50% when amiodarone is taken. Cardarone also increases levels of flecainide, procainamide and quinidine.

Missed dose

If you missed a dose take it as soon as you remember, but not if it is almost time of the next intake by your schedule. If it occurred skip the missed dose. Do not try to compensate a missed dose by taking an extra one.


If you suspect that you took too much of the medication and experience extremely dizzy or light-headed, or fainting seek for immediate medical attention.


Keep Cordarone at room temperature, lower than 30 C (86 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. РђРїСѓ specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.