Generic Danazol
Danazol
Danazol is a synthetic steroid hormone used in treatment of endometriosis, fibrocystic breast disease, benign breast tumors, abnormally long periods, premenstrual syndrome, gynecomastia.
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50 mg x 30 pills
$163.99
$5.47
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50 mg x 60 pills
$273.99
$4.57
$54.00
50 mg x 90 pills
$373.99
$4.16
$117.90
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100 mg x 30 pills
$199.99
$6.67
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100 mg x 60 pills
$333.99
$5.57
$66.00
100 mg x 90 pills
$454.99
$5.06
$144.90
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200 mg x 30 pills
$307.99
$10.27
$0.00
200 mg x 60 pills
$603.99
$10.07
$12.00
200 mg x 90 pills
$897.99
$9.98
$26.10
Product Description
Danazol is an effective treatment for endometriosis, and has the same effectiveness as the other hormonal treatments. Dznazol effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue changes in vision dark urine decrease in Danazo, size hair loss or unusual hair growth headache irregular vaginal bleeding, spotting nausea, Dxnazol, stomach pain redness, blistering, peeling or loosening of the skin, including inside the mouth unusual bleeding or bruising unusual swelling of feet or ankles unusually weak or tired voice changes weight gain yellowing of the skin or eyes Side effects that usually do not require medical attention report to your doctor or health care professional if they continue or are bothersome : acne, oily skin hot flashes, sweating mood changes vaginal dryness or irritation This list may not describe all possible side effects. However, some of the androgenic side effects are sometimes irreversible [4,5], such as:. Study Description. Progestogens and antiprogestogens. Introduction: Myelodysplastic syndromes MDS are a heterogeneous group of clonal hematological disorders characterized by ineffective hematopoiesis and variable degrees of peripheral cytopenias. Wolters Kluwer Health. Available for Android and iOS devices. Aglepristone Mifepristone. Kurman 17 April Primary Immunodeficiency. Short telomeres are the major prognostic risk factor for clonal evolution to myelodysplasia and acute leukemia. Androgens and antiandrogens. You should visit your gynaecologist about six to eight weeks after beginning treatment with danazol to discuss how the treatment is progressing. Hereditary Angioedema. Royal College of Obstetricians and Gynaecologists. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Close Abstract. Best wishes. What side effects can this medication cause?
Common use

Danazol is a synthetic steroid produced from ethisterone. This medication suppresses synthesis of

gonadotrophic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by pituitary gland in men and women. In women this drug inhibits activity of the ovaries, ovulation, leads to atrophy of the endometrium. The medication is used to treat to treat endometriosis (associated with sterility), fibrocystic breast disease, to prevent attacks of inherited angioedema, benign breast tumors (fibro-cystic breast), menorrhagia (abnormally heavy and prolonged menstrual period), premenstrual syndrome, primary premature puberty, gynecomastia.



Dosage and direction

The common recommended dose in adults is 200-800 mg a day divided in 2-4 intakes. Treatment starts on the first day of the menstrual cycle. To treat severe endometriosis the initial daily dose is 400 mg, later the dose may be increased to 800 mg by your physician. Treatment continues for six months. In children with premature puberty the dose is 100-400 mg.



Precautions

Cautiousness should be exercised in patients with diabetes mellitus, epilepsy, migraine. Use reliable and effective forms of contraception while you are on Danazol such as a condom or diaphragm with spermicide gel or inserts as hormonal forms of contraception may turn out non effective. Dose correction is needed in patients with diabetes. Take this drug according to the instructions of your doctor. Do not exceed the recommended dose. Women may need to start Danazol during their menstrual period. This medication may change results of some medical tests, inform your doctor if you take this medication. Do not start or stop this medication without approval of your doctor, continue to take it even if you do not notice immediate positive results of treatment. If your symptoms do not improve in two months inform your doctor.



Contraindications

This medication cannot be used in patients with hypersensitivity to Danazol or its components, in pregnant and breastfeeding women, porphyria (activity of liver transaminases increases), liver or kidney failure, chronic heart failure, thromboembolism, androgen producing tumor, vaginal bleeding of unknown origin.



Side effects

The most common side effects include signs of allergy (hives, rash, facial swelling, difficulty breathing) and also sudden numbness or weakness, angina, sudden cough, wheezing, rapid breathing, fast heart rate, sudden problems with vision, speech, or balance, confusion, swelling, feeling short of breath, rapid weight gain, headache, vision problems, ringing in the ears, dizziness, nausea, loss of appetite, dark urine, pain behind the eyes, stomach pain, jaundice.



Drug interaction

Danazol increases effects of anticoagulants of cumarine series and derivatives of indandione such as the risk of bleeding. Danazol decreases effects of insulin and oral hypoglycemic drugs by affecting metabolism of carbohydrates, increasing blood sugar levels Danazol inhibits metabolism of carbamazepine and increase its blood levels increases blood concentrations of cyclosporine and tacrolimus hereby increasing risk of nephrotoxicity. Danazol also increases serum levels of glucagon.



Missed dose

Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.



Overdose

This medication is not likely to produce life-threating symptoms. The most common effects of overdose are weight gain, menstrual problems, increased acne or facial hair growth, breast changes.



Storage

Store at room temperature between 20-25 C (68-77 F). Store away from moisture, heat, and sunlight. It is not recommended to store in a bathroom and places available for children.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Doxycycline

Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.