Generic Esidrix (Hydrochlorothiazide)
Esidrix helps to prevent your body from absorbing too much salt, which can cause fluid retention. Also the medicine is used for treating high blood pressure (hypertension).
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Common use

Esidrix is a thiazide diuretic (water pill) that helps to prevent your body from absorbing too much salt, which can cause fluid retention. The fluid retention can occur in people with congestive heart failure, cirrhosis of the liver, or kidney disorders, or edema caused by taking estrogens o steroids. Also the medicine is used for treating high blood pressure (hypertension).

Dosage and directions

Take Esidrix exactly as it was directed by your doctor.Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication.

To be sure this medication is not causing harmful effects, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.

Your blood and urine may both be tested if you have been vomiting or are dehydrated. If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms. Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.


Before taking Esidrix discuss with your doctor if you have kidney or liver disease, gout, allergies or asthma, diabetes or allergy to sulfa drugs.


Do not use the medicine if you have allergy to hydrochlorothiazide or if you are unable to urinate. Before using Esidrix, tell your doctor if you have liver or kidney disease, asthma or allergies, gout, diabetes or if you have allergy to sulfa drugs. Avoid drinking alcohol and becoming overheated or dehydrated during exercise in hot weather.

Possible side effects

Seek urgent medical help if you fell these sever side effects:allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using the medicine if you have signs of the following severe side effects: dry mouth, thirst, nausea, vomiting; feeling weak, drowsy, restless, or light-headed; fast or uneven heartbeat; muscle pain or weakness; numbness or tingly feeling; a red, blistering, peeling skin rash; or nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects are: mild stomach pain, diarrhea, constipation or blurred vision.

Drug interaction

Before taking Esidrix tell your doctor if you are using lithium, steroids (prendisone), digoxin (Lanoxin), cholestyramine ( Questran, Prevalite) or colestipol (Colestid), other blood pressure medications, insulin or diabetes medicine taken by mouth, NSAIDs such as apirin, ibuprofen, diclofenac, indometacin, naproxen, piroxicam, nabumetone, etodolac and others.

Missed dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


Seek urgent medical attention if you think you have overdosed this medicine. Overdose symptoms may include nausea, weakness, dizziness, dry mouth, thirst, and muscle pain or weakness.


Store at room temperature away from heat, light, and moisture.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.