Generic Grisactin (Griseofulvin)
Grisactin is an antifungal medication which is used to treat fungal infections of the skin, hair, and nails.
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Common use

Grisactin is an antifungal medication which used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete's foot, and barber's itch. This drug does not treat infections due to bacteria or yeast. Crisactin just stopping the growth of fungi.

Dosage and direction

Take it orally with full glass of water or with food.

The recommended dose for adults is:

PO 500 to 1,000 mg micro-size (330 to 750 mg ultramicrosize) in single or divided doses during for several weeks.

The recommended dose for children is:

PO 11 mg microsize/kg/day (125 to 500 mg) or 7.3 mg ultramicrosize/kg/day (82.5 to 330 mg).

The length of treatment depends from the type of infection and consist:

1. Tinea corporis: 2-4 weeks

2. Tinea capitis: 4-6 weeks or longer

3. Tinea pedis: 4-8 weeks

4. Tinea unguium: 3-6 months or longer

Note: this instruction presented here just for review. It's very necessary to consult with your doctor before using. It help you to get best results.


Before using this medicine, consult your doctor or pharmacist if you have: a certain blood disorder (porphyria), severe liver disease (liver failure). Don't forget to tell your medical history, especial if it include lupus. Do not driving while you taking Crisactin because it make you dizzy or less alert. Do not drink alcohol, this may cause a fast heartbeat and flushing of the skin. Avoid the sun, use a sunscreen and wear protective clothing when outdoors. Grisactin should not be used during pregnancy, becoming pregnant or lactating without doctor's advice. Do not use before breast-feeding without doctor's advice.


Grisactin is not allowed to people with hepatic disease, porphyria (interferes with porphyrin metabolism), hypersensitive to griseofulvin or any componentof this dug.

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:

white patches in your mouth (thrush/yeast infection);

nausea, vomiting, or diarrhea;

headache, dizziness, or tiredness;



numbness or tingling in your hands or feet; or

menstrual irregularities.

If you experience one of them stop using Serevent and tell your doctor as soon as possible. Also consult with your doctor about any side effect that seems unusual.

Drug interaction

Grisactin interact with follow drugs :

barbiturate medicines for sleep or seizures

female hormones, like estrogens or progestins and birth control pills


Also note that interaction between two medications does not always mean that you

must stop taking one of them. As usual it affects the the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usually dose next day in the same regularly time.


Symptoms of Grisactin overdose are not known well, but most possible may include: include nausea, vomiting, diarrhea, headache, numbness and tingling, and confusion. If you experience one of them call your doctor immediately.


Store at room temperature between 59-77 degrees F (15-25 degrees C) away from light and moisture, kids and pets. Do not use after expiration term.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.