Malegra DXT (Sildenafil/Duloxetine)
Malegra DXT
Malegra DXT is a combination drug, having both Sildenafil and Duloxetine in its compound. Malegra DXT provides its patient with longer sex before ejaculation, treating premature ejaculation problems.
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Product Description

Malegra DXT - logically

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There is no need to take this drug constantly as the way it works is that after you have taken one single dose you should, in a short period of time find that you can get an erection and that the erection should remain as the effects of the drug kick in. Malegra DXT can interact with other drugs and cause undesirable adverse effects.

Common use

Malegra DXT is a combination drug, having both Sildenafil and Duloxetine in its compound. The therapeutic effect is great: aside from long and stable erection, usual for Sildenafil drugs, Malegra DXT provides its patient with longer sex before ejaculation, treating premature ejaculation problems.

Dosage and direction

Malegra DXT pill contains 100 mg of Sildenafil + 30 mg of Duloxetine, so the overall dose of active substances is 130 mg per tablet. The recommended dose is just one tablet of Malegra DXT at least an hour before planned sexual activity. The effect of the drug lasts for 6 hours and more, making your sexual experience rich and pleasant.


Malegra DXT is not recommended to men younger than 18 years or older than 60 years old for possible complications. If you take Malegra DXT, you shouldn’t chew the tablet, but swallow it wholly. The drug does not protect the user from sexually transmitted diseases or AIDS. It’s dangerous to mix Malegra DXT with alcohol.


Cardiovascular diseases, blood pressure issues and liver problems make the use of Malegra DXT dangerous for health. Please, don’t use Sildenafil + Duloxetine combination in case you have any of those problems without a proper consultation with your doctor.

Possible side effect

Though Malegra DXT is commonly safe and causes minor to none adverse effects, you should take care using it. The best option is to consult your doctor for proper administration of the drug and a medical advice on its use. However, sometimes patients experience headaches, back pain, flushing and indigestion after they take the drug.

Drug interaction

Malegra DXT has the same interactions as Sildenafil + Duloxetine. Erythromycin and cimetidine cause the effect of Malegra DXT last longer, which is not useful. Taking the drug together with other alpha blockers, you expose yourself to a risk of low blood pressure.

Missed dose

You shouldn’t worry about a missed dose of Malegra DXT, because it’s a single-time action medication. You don’t have to take the drug regularly: you can only use it when you need its effect.


Don’t overdose Malegra DXT! The maximum positive effect of the drug is achieved with just one tablet. Further increase in dose can lead to low blood pressure and other complications. If you feel dizziness, drowsiness or weakness after taking Malegra DXT, consult your medical care specialist on the further use of the drug.


Keep Malegra DXT blister in a dark dry place at room temperature.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.