Generic Maxaquin (Lomefloxacin)
Maxaquin
Maxaquin is used to treat bacterial infections. It may also be used for treating other conditions as determined by your doctor.
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400 mg x 30 pills
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400 mg x 60 pills
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400 mg x 90 pills
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400 mg x 120 pills
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Product Description
Therapeutic urine levels could be found in patients up to 48 h after end of infusion. Rights and permissions Reprints Maxaquin Permissions. Namespaces Article Talk. NY [1-ethyl-6,8-difluoro-1,4-dihydro 3-methylpiperazinyl oxo quinolinecarboxylic acid hydrochloride] is a new difluorinated quinolone characterized by the presence of a C-methyl group at the 3 position of the piperazine moiety. The mean peak level in serum, 4. This method has been used successfully in pharmacokinetic studies in humans. Information on overdosage in humans is limited. Samples from two volunteers were also assayed by high-performance liquid chromatography. Other quinolones also produce erosions of cartilage of weight-bearing joints and other signs of arthropathy in juvenile animals of various species. Approved Use Bacterial conjuctivitis due to susceptible organisms. This drug maybe used to treat other diseases and conditions. The brand name of this medication is discontinued, but generic versions may be available. About 1. Get Best Deal. Histopathologic examination of the weight-bearing joints of these animals revealed permanent lesions of the cartilage. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Clinical evaluation of ophthalmic lomefloxacin 0. Samples from two volunteers were also assayed by high-performance liquid chromatography. In three pharmacokinetic studies including 46 normal, healthy subjects, theophylline clearance and concentration were not significantly altered by the addition of lomefloxacin. In the present article, this Power Approach which in practice usually consists of testing the hypothesis of no difference at level 0. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Previous Abstract Next Abstract. A report of "intermediate" indicates that the result should be considered equivocal, and, if the organism is not fully susceptible to alternative clinically feasible drugs, the test should be repeated. Clinical evaluation of ophthalmic lomefloxacin 0. Keep me logged in. This article has been saved into your User Account, in the Favorites area, under the new folder " ". Abanmi et al. Thought you might appreciate this item s I saw at Clinical Nurse Specialist. Show more authors. Daily news summary. No account? Shipilova, L. End Note. Chemotherapy ; 36 suppl 2 : — There was cross-resistance between the quinolone group of antimicrobial agents. Treatment with antimicrobial agents alters the normal flora of the colon and may permit overgrowth of clostridia. However, until more information becomes available, lomefloxacin, like all other quinolones, should be used with caution in patients with known or suspected CNS disorders, such as severe cerebral arteriosclerosis, epilepsy, or other factors that predispose to seizures. Convulsions have been reported in patients receiving Maxaquin. The interday CV ranged from 1. Therapeutic urine levels could be found in patients up to 48 h after end of infusion. In 16 healthy elderly volunteers 61 to 76 years of age with normal renal function for their age, the half-life of lomefloxacin mean of 8 hours and its peak plasma concentration mean of 4. Maxaquin is available as a film-coated tablet formulation containing mg of lomefloxacin base, present as the hydrochloride salt. Lomefloxacin was comparable in activity to fleroxacin and ofloxacin, but it was less active than ciprofloxacin. See Adverse Reactions. Psychiatric: insomnia, nervousness, somnolence, anorexia, depression, confusion, agitation, increased appetite, depersonalization, paranoid reaction, anxiety, paroniria, abnormal thinking, concentration impairment. Lomefloxacin has been shown to be active against most strains of the following organisms both in vitro and in clinical infections: See Indications and Usage. By using this site, you agree to the Terms of Use and Privacy Policy. Return Home Inxight: Drugs. The substance therefore is a suitable remedy for urinary infections in dialysis patients as well. Keep me logged in. Sample preparation involves protein precipitation with acetonitrile.
Common use

Maxaquin is a fluoroquinolone antibiotic. Maxaquin is used to treat bacterial infections. It works by killing sensitive bacteria by stopping the production of essential proteins that the bacteria need to survive .It may also be used for treating other conditions as determined by your doctor.



Dosage and directions

Use Maxaquin as directed by your doctor. The drug may be taken with or without food, with a full glass of water. Also, drink several additional glasses of water each day. Maxaquin should be taken 2 hours before or 4 hours after the following medicines: antacids containing aluminum, calcium, or magnesium; didanosine; iron salts (eg, ferrous sulfate); sucralfate; or zinc salts (eg, zinc sulfate). Maxaquin works best if it is taken at the same time each day.



Precautions

Maxaquin may cause dizziness or lightheadedness. Be carefully driving, working with machinery or doing activit which requires concetration of attention or don't perform such activity until you make sure you ca do it safely. Avoid drinking alcohol.

Maxaquin may cause increased sensitivity to the sun. Avoid exposure to the sun. To reduce the risk of sensitivity to the sun, take Maxaquin at least 12 hours before exposure to the sun (in the evening).



Contraindications

It is not recommended to use the drug in children younger than 18 years of age.

If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Maxaquin during pregnancy. It is unknown if Maxaquin is excreted in breast milk. Do not breast-feed while taking Maxaquin.



Possible side effects

Check with your doctor if any of these most common side effects persist or become bothersome: diarrhea; headache; dizziness; nausea.

Seek medical attention immediately if any of these severe side effects occur:

severe allergic reactions (rash; hives; difficulty breathing; joint pain or swelling; pain, tingling, or numbness in the hands or feet; anxiety; bloody stools; burning sensations; confusion; convulsions; seizures; severe or continuing diarrhea; tightness in the chest; swelling of the mouth, face, lips, or tongue;severe sunburn; skin burning, redness, swelling, blisters, or itching; stomach pain/cramps; tendon pain; tremors; vaginal irritation or discharge; weakness.



Drug interaction

Tell your doctor if you are taking any other medicines, especially of:

*Typhoid live vaccine because Maxaquin may descrease its effectiveness

*Droperidol or foscarnet because Maxaquin may increase heir actions and side effects



Missed dose

If you miss a dose of Maxaquin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.



Overdose

If overdose is suspected, contact your local poison control center or emergency room immediately.



Store

Store Maxaquin between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Maxaquin out of the reach of children and away from pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Doxycycline

Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.