Generic Myambutol (ethambutol hydrochloride)
Myambutol is an adjuvant for treatment of pulmonary tuberculosis.
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Product Description

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Common use

Myambutol is an antibiotic used to treat tuberculosis. It is active only against actively propagating cells of Mycobacterium tuberculosis. Myambutol inhibits synthesis of bacterial RNA, affects cell metabolism, stops reproduction and death of bacteria. Myambutol can be used against mycobacteria resistant to streptomycin, isoniazid, ethionamide, kanamycin.

Dosage and directions

Follow all recommendations of your doctor about this medication. Do not start or stop it without your doctor's permission. To prevent stomach upset take with a meal or milk. Kidney failure requires correction of the dose.


Myambutol unless combined with one or more other tuberculosis medicines may cause fast growth of resistant bacterial strains.


This medicine is contraindicated in patients with hypersensitivity to it, individuals with optic neuritis, cataract, diabetic retinopathy, inflammatory diseases of eyes, gout, in children under 13 years of age, in pregnant and breastfeeding women, patients with chronic kidney failure.

Possible side effect

The first most common reactions of organism to Myambutol are stomach upset, dizziness, fatigue, and headache. These symptoms should disappear when the body accustoms to the medication. In case of worsening of the symptoms notify your doctor immediately. If any signs of allergy develop notify your doctor promptly: rash, swelling, numbness or tingling of the hands or feet. Any vision changes, inability to distinguish green and red colors, sudden color blindness, blurred vision require urgent doctor's attention. To avoid permanent and even fatal liver disease tell your doctor immediately about persistent or severe nausea, vomiting, stomach/abdominal pain, dark urine, jaundice.

Drug interaction

Myambutol increases effects of anti-tuberculosis medications, neurotoxicity of cyprofloxin, carbamazepine, asparaginase, amynoglycosides, Li+ salts, imipenem, metotrexat, quinine.

Missed dose

If you miss a dose, take it as soon as you remember unless it is almost time of your next dose. If it is near the time of the next dose, skip the missed dose and return dosing schedule. Do not double the dose to make up the missed dose.


Symptoms of overdose are unknown. If you suppose that too much of Myambutol was taken seek immediate medical attention.


Store at room temperature in a tight container, away from moisture and humidity.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.