Generic Nimotop (Nimodipine)
Nimotop
Nimotop is a calcium channel blocker used to treat to prevent brain damage caused by reduced blood flow due to aneurysm, etc.
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30 mg x 30 pills
$51.99
$1.73
$0.00
30 mg x 60 pills
$90.99
$1.52
$12.60
30 mg x 90 pills
$127.99
$1.42
$27.90
30 mg x 120 pills
$157.99
$1.32
$49.20
30 mg x 180 pills
$218.99
$1.22
$91.80
30 mg x 240 pills
$266.99
$1.11
$148.80
30 mg x 360 pills
$363.99
$1.01
$259.20
Product Description
As a Nimohop channel blocker, nimodipine may have the potential to exacerbate heart failure in susceptible patients or to interfere with A-V conduction, but these events were not observed. Important : if you experience any unusual or unexplained bleeding or bruising, speak with your doctor straightaway. Br J Clin Pharmacol. Daily news summary. However, whether or not the arteriographic methodology utilized was adequate to detect a clinically meaningful effect, if any, on vasospasm is unknown. However, dantrolene's limited penetration into the CNS hampers its effectiveness as a neuroprotective agent. The rest of the parts of the lesions were T1 hyperintensity, T2 hyperintensity, and diffusion-weighted imaging DWI hyperintensity, which indicate cortical laminar necrosis. Priority date: The concomitant use of oral nimodipine Nimotop the antiepileptic drugs phenobarbital, phenytoin or carbamazepine is contraindicated as efficacy of nimodipine capsules could be significantly reduced. Join the discussion on the forums. Nimodipine was dosed 60mg every 4 hours. Find jobs. Nimotop nimodipine is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured intracranial berry aneurysms regardless of their post-ictus neurological condition i. Chronic use of intranasal dantrolene did not impair olfaction or motor function in these mice. Latest News. True Nimotop. Vascular imaging reveals alternating cerebral vasoconstriction and vasodilation that normalizes within 12 weeks. Used in the treatment of cardiovascular diseases. Dramatical improvements in Nimptop dissolution rate of NMP were achieved by the ingenious combination of the two polymers. Nimotop novel Njmotop is Njmotop in this study. Manufacturer Back to Top. The condition has responded to conservative management. FDA alerts for all medications. G Nimohop Prescription drugs Drugs available to the public on Nimoyop only Obat Keras. Nimodipine has been shown, in 4 randomized, double-blind, placebo-controlled trials, to reduce the severity of neurological deficits resulting from vasospasm in patients who have had a recent subarachnoid hemorrhage SAH. Nimotop Dosage Back to Top. Protect from light. While the initial relapsing-remitting stage of MS can be treated effectively with immune modulatory and immunosuppressive drugs, the subsequent progressive stage has remained largely untreatable. Did you experience many side effects while taking this drug? Drugs, which are known inhibitors of the cytochrome P 3A4 system and therefore may lead to increased plasma concentrations of nimodipine are, e. In Europe, Nimotop was observed to occasionally intensify the effect of antihypertensive compounds taken concomitantly by patients suffering from hypertension; this phenomenon was not observed in North American clinical trials. Nimotop is given orally in the form of ivory colored, soft gelatin 30 mg capsules for subarachnoid hemorrhage. This is not a complete list of Nimotop drug interactions. Thrombocytopenia; allergic reaction, rash; headache; tachycardia; hypotension, vasodilatation; nausea. The purpose of this paper was to study the protective effect of paeoniflorin on acute cerebral ischemia. Cited by: 2 articles PMID: Any Deficit Due to Spasm. Each Nimotop colored, soft gelatin Nimotop capsule is imprinted with the word Nimotop and contains 30 mg of nimodipine. Drugs A to Z. No formal studies have been performed to investigate the potential interaction between nimodipine and nefazodone. The residue level in the body was never more than 1. Adverse experiences were reported by 92 of patients with subarachnoid hemorrhage Concomitant administration of nimodipine with antidepressants such as fluoxetine and nortryptyline should be avoided as elevated nimodipine levels may occur. Product Characteristics. Dosage should be reduced to one 30 mg capsule every 4 hours with close monitoring of blood pressure and heart rate; if necessary, discontinuation of the treatment should be considered. Azithromycin, although structurally related to the class of macrolide antibiotic is void of CYP3A4 inhibition. Here we have set out to evaluate this nanomedical approach to deliver nimodipine selectively to acidic ischemic brain tissue. Combining electrophysiological, pharmacological, and computational approaches, we investigated the staircase PICs in serotonergic neurons of medulla in ePet-EYFP transgenic mice postnatal days In Europe, Nimotop was observed to occasionally intensify the effect of antihypertensive compounds taken concomitantly by patients suffering from hypertension; this phenomenon was not observed in North American clinical trials. Blood levels of nimodipine may be increased with concomitant administration of cimetidine or the anticonvulsant sodium valproate.
Common use

Nimotop is a nimodipine. It can prevent or eliminate spasm of vessels caused by various drugs such as serotonin or histamine. Due to its the high lipophility penetrates the blood-brain barrier (BBB). Nimotop improves stability and functional capacity of neurons. The medication also affects positively learning ability and memory by blocking of Ca2+-channels in certain brain areas, such as the hippocampus and cerebral cortex.



Dosage and direction

Take the medication orally exactly as prescribed to you. Do not exceed the recommended dose. Take on an empty stomach with a full glass of water one hour before or two hours after a meal. To get the most benefit of the drug take it regularly.



Precautions

Cautiousness should be exercised in individuals with severe bradycardia, liver failure, mild or moderate hypotension, myocardial infarction associated with the failure of left ventricular, intracranial hypertension, generalized edema of the brain tissue. Avoid drinking of grapefruit juice while you ar eon Nimptop. When Nimptop is used with rifampicin effectiveness of the former can be reduced. Simultaneous adminitration of nimodipine with cimetidine or valproic acid may lead to increased concentrations of nimodipine in blood serum. Beta-blockers used together with Nimptop may cause considerable drop in blood pressure. Procainamide, quinidine used together with Nimptop may significantly increase the risk of elongation of the QT interval.



Contraindications

The medication should not be used in patients with hypersensitivity to the medication, severe hypotension, pregnant and breastfeeding women.



Possible side effect

In case of severe signs of allergy seek immediate medical care: skin rash, difficulty breathing, facial swelling, hives. Inform your doctor as soon as possible also if you experience fainting or severe dizziness, unusually fast or slow heartbeats, easy bruising or bleeding, unusual weakness, swelling in your legs or ankles.



Drug interaction

Inform your doctor about all prescribed, over-the-counter medications, herbal products and food supplements you use. Combined use of nimodipine and Fluoxetine leads to increased concentrations of nimodipine in blood serum. Prolonged use of nimodipine with Nortriptyline results in a slight increase in serum levels of nimodipine. If phenobarbital, phenytoin or carbamazepine were used for a long time before nimodipine they may reduces its bioavailability.



Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose.



Overdose

Symptoms of overdose which may need you to apply immediately for professional medical attention are: chest pain, dizziness, fainting, weakness, shortness of breath, an unusually fast or slow heartbeat, confusion, slurred speech, or coma.



Storage

Store in a dry tight container away from sunlight at room temperature between 15-30 C (59-86 F) away from children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Doxycycline

Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.