Generic Thorazine (Chlorpromazine)
Thorazine is used to treat certain mental or mood disorders.
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50 mg x 30 pills
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50 mg x 90 pills
50 mg x 120 pills
50 mg x 180 pills
50 mg x 360 pills
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100 mg x 30 pills
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Product Description
Class III antiarrhythmic agents such as amiodarone and sotalol. Sign in to make a comment Sign in to your personal Thorazjne. Store it at room temperature and away from excess heat and moisture not in Thrazine bathroom. To be approved a drug will need clinical trial data that show that it is safe, effective and compares favourably to existing treatments. The s saw several new classes of medication enter psychiatric practice including the Thlrazine. Nevertheless, the antipsychotics played an important Thorazune as they provided Tohrazine effective treatment for schizophrenia and gave clinicians and managers the confidence to discharge patients and set up alternative community services. Agonists: BRL Ergolines e. Chlorpromazine should not be used in pregnant women, or those likely to become pregnant, unless the expected benefit outweighs any potential risk. Psychiatric Dysphoria, catatonic excitement. Interactive image. Appropriate antibiotic therapy should be instituted for any respiratory infections. The trunk and limbs are less frequently involved. The introduction of antipsychotics and other psychiatric drugs during the s had a major impact on the way that psychiatric illness was viewed by clinicians and scientists. In hot climates, patients are particularly at risk if they are overweight, physically active, and taking high doses of neuroleptics and anti-parkinsonian agents. Cardiovascular Arrhythmias, hypertensive crisis following abrupt withdrawalA-V block, ventricular tachycardia, QT interval prolongation and fibrillation. Assaultive or destructive behavior is rapidly controlled. The medicine can also make your skin more sensitive to sunlight. If the hiccups do not stop after 3 days of treatment, a different medication should be used. Uses of Thorazine Back to Top. Xenobiotic-sensing receptor modulators. Chlorpromazine comes as a tablet to take by mouth. There is inadequate animal data regarding reproductive toxicity with chlorpromazine by parenteral route. Do not stop taking chlorpromazine without talking to your doctor. The Creation of Psychopharmacology. Your Personal Message. When chlorpromazine is used to relieve hiccups, it is usually taken times a day for up to 3 days or until the hiccups stop. These include severe muscle stiffness, fever, unusual tiredness or weakness, fast heartbeat, difficulty breathing, increased sweating, loss of bladder control, and seizures neuroleptic malignant syndrome. Chlorpromazine has tentative benefit in animals infected with Naegleria fowleri. Back Next. Fortunately, occurrences are rare. Thorazine Dosage. Thorazinw and behavior: Tuorazine introduction to behavioral Thorasine 6th ed. This assumption arose from the dopamine hypothesis that maintains that both schizophrenia and bipolar disorder are a result of excessive dopamine activity. As the underlying defect in myasthenia gravis is a decrease in the number of available acetylcholine Tborazine at neuromuscular junctions, chlorpromazine should be avoided Thorazine myasthenia gravis due to its strong antimuscarinic effects. Prostate Hypertrophy Chlorpromazine should be avoided in patients with prostate hypertrophy due to the anticholinergic effects of phenothiazines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Rare 0. Springer Nature. Chlorpromazine is also used to control nausea and vomiting, to relieve hiccups that have lasted one month or longer, and to relieve restlessness and nervousness that may occur just before surgery. It is advised that maximum daily dosage should not exceed 40 mg. Eye deposits occurred in the anterior segment of the eye from drug accumulation; however, the deposits usually did not have impact on sight. Therefore, chlorpromazine with respect to its effects on dopamine and serotonin receptors is more similar to the atypical antipsychotics than to the typical antipsychotics. Patients who develop pyrexia, along with clouding of consciousness and rigidity should cease medication and undergo immediate investigation, as these are the early symptoms of the neuroleptic malignant syndrome, a potentially lethal adverse effect of major tranquillisers see ADVERSE EFFECTS. Save Preferences. Now 20, she has been on 6 different antipsychotics. Antagonists: Metitepine methiothepin. Chlorpromazine may cause side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Effects on Laboratory Tests The presence of phenothiazines may produce false positive phenylketonuria PKU test results. Your doctor will probably decrease your dose gradually. Eventually, dopamine production of the neurons will drop substantially and dopamine will be removed from the synaptic cleft. Today insulin coma and leucotomy are not used at all in psychiatry. Thorazine may cause problems in newborns following delivery if it's taken during the last months of pregnancy. Available for Android and iOS devices. Since then over two hundred clinical trials of antipsychotics in schizophrenia have been published. Therefore, chlorpromazine with respect to its effects on dopamine and serotonin receptors is more similar to the atypical antipsychotics than to the typical antipsychotics. Muscarinic acetylcholine receptor modulators. In addition, both CBT and family therapy, when added to standard treatment, have been shown to reduce the risk of hospitalisation compared to standard treatment alone. There appears to be a dose-dependent risk for seizures with chlorpromazine treatment. Chlorpromazine is occasionally used off-label for treatment of severe migraine. Endocrine Hyperthermia, hypothermia, lactation and moderate breast engorgement in females on Thorazind doses, false-positive pregnancy Thorzaine, amenorrhoea, gynecomastia, hypoglycaemia, glycosuria. The antiemetic effects of chlorpromazine may mask signs of overdosage of toxic drugs or obscure the diagnosis of conditions such as intestinal obstruction and brain tumour. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular eg, heart failure, sudden death or infectious eg, pneumonia in nature. Thorazine can also be used to treat nausea and vomiting. The presumed effectiveness of the antipsychotic drugs relied on their ability to block dopamine receptors. Xenobiotic-sensing receptor modulators. Tardive dyskinesia a movement disorder may occur and may not go away after you stop using the medicine. Ocular Blurred vision, photophobia, miosis, mydriasis, corneal deposits. Dopamineunable to bind with a receptor, causes a feedback loop that causes dopaminergic neurons to release more dopamine. Archived from the original on 24 July If you are taking chlorpromazine to treat schizophrenia or another psychotic disorder, chlorpromazine may control your symptoms Thorazne will not cure your condition. The easiest way to lookup drug information, Thrazine pills, check interactions and set up your own personal medication records. Despite this, Laborit continued to push for testing in psychiatric patients Thrazine early Its high Thoraziine of lipophilicity fat solubility allows it to be detected in the urine for up to 18 months. Common side effects Thodazine Thorazine include dry mouth, nausea, constipationand Thoarzine blood pressure. Subscribe to Drugs. We comply with the HONcode standard for trustworthy health information - verify here. Observational studies suggest that conventional or first-generation antipsychotic agents also may increase mortality in such patients. Psychiatrists were reluctant initially, but on January 19,it was administered alongside pethidine, pentothal and ECT to Jacques Lh. Taken together they show that antipsychotics lead to a greater improvement in the symptoms of schizophrenia than treatment with a placebo i. Leave a Reply Cancel reply Your email address will not be published. Retrieved 14 February There is a need for more effective medicines with fewer side effects and more research into talking treatments and the long-term outcome of schizophrenia with different treatment approaches. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Chlorpromazine may make your skin sensitive to sunlight. We also need a better understanding of the causes of psychosis to help with its prevention. Chlorpromazine is not approved by the Food and Drug Administration FDA for the treatment of behavior problems in older adults with dementia.
Common use

Thorazine is used to treat certain mental or mood disorders such as schizophrenia, anxiety, the manic phase of manic-depressive disorder, and restlessness, before surgery, porphyria, severe conduct and behavioral disorders in children, nausea and vomiting, and severe hiccups. It can be used to treat symptoms associated with tetanus. Its active component is phenothiazine. It blocks dopamine receptors in the brain.

Dosage and directions

Use Thorazine as prescribed by your doctor. Take it by mouth with or without food. It can cause stomach upset, so take it with food to reduce stomach irritation.


Before taking Thorazine tell your doctor about all the conditions you may have, especially if you are pregnant, planning to become pregnant or breastfeeding, if you are taking any medicines prescribed and not prescribed, herbal products or dietary supplement, if you have allergies to medicines, food, etc, if you have history of heart problems, blood problems, high blood pressure, liver problems such as cirrhosis, kidney problems, seizures or epilepsy, Parkinson disease, enlarged prostate gland, Reye syndrome, alcohol abuse or if you consume more than 3 alcoholic drinks per day, if you have lung infections, asthma and other lung problems, glaucoma, increased pressure in the eyes or if you are have a risk of glaucoma.


Do not take Thorazine if you have allergy to any of its components or similar medicines such as phenothiazines, if you have bone narrow problems or you are taking certain antiarrhythmic agents, dofetilide, astemizole, cisapride, ketolide antibiotics, macrolide antibiotics, pergolide, pimozide, terfenadine, ziprasidone, streptogramins.

Possible side effects

The most common possible side effects of Thorazine are dizziness, agitation, enlarged pupils, nausea, stuffy nose, jitteriness, dry mouth, drowsiness.

Severe side effects include: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in menstrual period; changes in sexual ability; dark urine; difficulty swallowing; drooling; fainting; fast or irregular heartbeat; fever, chills, or sore throat; involuntary movements or spasms of the arms and legs, tongue, face, mouth, or jaw; mask-like face; muscle restlessness; prolonged or painful erection; restlessness; seizures; shuffling walk; sleeplessness; stiff or rigid muscles; stomach pain; sweating; trouble urinating; unusual eye movements or inability to move eyes; unusual mood or mental changes, including lack of response to your surroundings; vision changes; weakness of arms or legs; yellowing of the skin or eyes.

Drug interaction

Tell you doctor about all the medicines prescribed and not prescribed you may take especially about:

*Thiazide diuretics (eg, hydrochlorothiazide) because they may increase the risk of Thorazine's side effects

*Barbiturates (eg, phenobarbital), hydantoins (eg, phenytoin), or narcotic pain medicines (eg, codeine) because the risk of their side effects may be increased by Thorazine

*Arsenic, astemizole , beta-blockers (eg, propranolol), certain antiarrhythmic agents (eg, quinidine), cisapride, dofetilide, droperidol, epinephrine, haloperidol, ketolides (eg, telithromycin), macrolide antibiotics (eg, erythromycin), pimozide, quinolone antibiotics (eg, ciprofloxacin), streptogramins (eg, quinupristin), terfenadine, or ziprasidone because the risk of side effects, such as racing heartbeat, dizziness, fainting, and life-threatening irregular heartbeat leading to unconsciousness, may be increased by Thorazine

*Anticholinergics (eg, atropine) because they may decrease Thorazine's effectiveness

*Anticoagulants (eg, warfarin), guanethidine, and pergolide because their effectiveness may be decreased by Thorazine

Missed dose

If you miss a dose of Thorazine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.


Symptoms of overdose of Thorazine are twitching, deep sleep or loss of consciousness, seizures, tremors, restlessness, muscle spasms.


Store Thorazine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container away from heat, moisture, and light. Do not store in the bathroom. Keep Thorazine out of the reach of children and away from pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.