Generic Toprol (Metoprolol)
Toprol
Toprol is a beta-blocker used to treat high blood pressure, heart pain, abnormal rhythms of the heart.
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25 mg x 30 pills
$26.99
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25 mg x 60 pills
$42.99
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25 mg x 90 pills
$57.99
$0.64
$23.40
25 mg x 120 pills
$69.99
$0.58
$38.40
25 mg x 180 pills
$93.99
$0.52
$68.40
25 mg x 360 pills
$169.99
$0.47
$154.80
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50 mg x 30 pills
$37.99
$1.27
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50 mg x 60 pills
$60.99
$1.02
$15.00
50 mg x 90 pills
$81.99
$0.91
$32.40
50 mg x 120 pills
$98.99
$0.82
$54.00
50 mg x 180 pills
$132.99
$0.74
$95.40
50 mg x 360 pills
$239.99
$0.67
$216.00
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100 mg x 30 pills
$47.99
$1.60
$0.00
100 mg x 60 pills
$76.99
$1.28
$19.20
100 mg x 90 pills
$103.99
$1.16
$39.60
100 mg x 120 pills
$123.99
$1.03
$68.40
100 mg x 180 pills
$167.99
$0.93
$120.60
100 mg x 360 pills
$301.99
$0.84
$273.60
Product Description
Amiodarone: Moderate Concomitant administration of metoprolol with amiodarone may cause additive electrophysiologic effects slow sinus rate or worsen AV blockresulting in symptomatic bradycardia, Toprol Xl arrest, and atrioventricular block. If heart rate is not controlled after 5 minutes, may repeat bolus oTprol 5 minutes to a maximum of 3 doses. Drug Class. Xll impairment. The FDA has approved beta blockers for the treatment of cardiac arrhythmias, hypertension, migraines, and others. Rasagiline: Moderate Additive hypotensive effects may be seen when monoamine oxidase inhibitors MAOIs are combined with antihypertensives. Propafenone: Major Pharmacologically, beta-blockers, like metoprolol, cause AV nodal conduction depression and additive effects are possible when used in combination with propafenone. Cimetidine: Moderate While not reported, clinicians should be alert to exaggerated metoprolol effects if the drug is given with cimetidine. Consuming alcohol while taking metoprolol may cause mild body rashes and is not advised. In another recent case, the F. Children: Not recommended. Bradycardia may be worsened when MAO-inhibitors are co-administered to patients receiving beta-blockers. However, there was no effect on the elimination half-life of metoprolol. Australian Government. Thiopental: Moderate General anesthetics can potentiate the antihypertensive effects of beta-blockers and can produce prolonged hypotension. Use caution with in-clinic dosing for erectile dysfunction ED and monitor for the effects on blood pressure. Take Toprol-XL exactly as prescribed by your doctor. Children and Adolescents 6 to 17 years. In addition, cocaine can reduce the therapeutic Toprkl of beta-blockers. Aspirin, Topol Carisoprodol; Codeine: Moderate Concurrent use of beta-blockers with aspirin and other salicylates may result in loss of antihypertensive activity due to inhibition of renal prostaglandins and thus, salt and water retention and decreased renal blood flow. Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine: Moderate Concurrent use of beta-blockers with aspirin and other salicylates may result in loss of antihypertensive activity Tporol to inhibition of renal prostaglandins and lX, salt and water retention and decreased renal blood flow. Nicardipine: Moderate Although concomitant therapy with Toprlo and metoprolol generally is well tolerated and can even Topfol beneficial in some cases by inhibiting reflex tachycardia induced by nicardipinemetoprolol can induce excessive bradycardia Tiprol hypotension. Geriatric patients are at increased risk XXl beta-blocker-induced hypothermia. Cabergoline: Major Because of its potential to cause coronary vasospasm, ergot alkaloids could theoretically antagonize the therapeutic effects of beta-blockers. Lacosamide: Moderate Use lacosamide with caution in patients taking concomitant medications that affect cardiac conduction, such as beta-blockers, because of the risk of AV block, bradycardia, or ventricular tachyarrhythmia. Insulin Degludec; Liraglutide: Moderate Increased frequency of blood glucose monitoring may be required when a beta blocker is given with antidiabetic agents. Upcoming Events 08 Apr. Patients should be advised to report increased effects of these medications, including hypotension or increased dizziness to their health care professional. In those men with significant corpora cavernosa venous leakage, hypotension might be more likely. Children: Not recommended. Baclofen: Moderate Baclofen has been associated with hypotension. You should not use Toprol-XL if you have a severe heart block greater than first degreesick sinus syndrome without a pacemaker, severe circulation problems, severe heart failure, a history of slow heart beats that caused fainting, or if you are allergic to Toprol-XL or metoprolol. Aspirin, ASA: Moderate Concurrent use of beta-blockers with aspirin and other salicylates may result in loss of antihypertensive activity due to inhibition of renal prostaglandins and thus, salt and water retention and decreased renal blood flow. Brand-name companies not only initially hold patents on the active ingredient but also on the way a pill releases a drug. Archived from the original on 12 March Crizotinib: Major Avoid coadministration of crizotinib with agents known to cause bradycardia, such as beta-blockers, to the extent possible due to the risk of additive bradycardia. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication TToprol. Nitroglycerin: Moderate Nitroglycerin can cause hypotension. Doxazosin: Moderate Orthostatic hypotension may be more likely if beta-blockers XXl coadministered with alpha-blockers. Email Address. Clinicians should monitor patients To;rol loss of beta blockade. Toprol-XL is used to treat angina chest pain and hypertension high blood pressure. However, Torol high blood pressure during pregnancy may cause complications such as diabetes or eclampsia dangerously high blood pressure that can lead to medical problems in both mother and baby. This medicine may cause changes in blood sugar levels. The risk of peripheral ischemia, resulting in cold extremities or gangrene, has been reported to be increased when ergot alkaloids are coadministered with selected beta-blockers, including propranolol, a beta-blocker commonly used for migraine prophylaxis. Using these drugs with metoprolol could increase the levels of metoprolol in your body. While beta-blockers may have negative effects on glycemic control, they reduce the risk of cardiovascular disease and stroke in patients with diabetes and their use should not be avoided in patients with compelling indications for beta-blocker therapy when no other contraindications are present. Sports Health. Diazoxide: Moderate Additive hypotensive effects can occur with the concomitant Tlprol of diazoxide Tkprol other antihypertensive agent. In patients with stable, chronic Toprrol failure, however, some beta-blockers, including metoprolol, given in low doses have been documented to be beneficial. Propofol: Major General anesthetics can potentiate the antihypertensive effects of beta-blockers and can produce prolonged hypotension. The dosage used in these studies ranged from to mg daily. Extended-release products are given once daily. Heart Failure. In addition, limited data suggest that bradycardia is worsened when MAOIs are administered to patients receiving beta-blockers. Clonidine: Major Monitor heart rate in patients receiving concomitant clonidine and agents known to affect sinus node function or AV nodal conduction e. Combined with metoprolol, calcium channel blockers may slow your heart rate even more. To help avoid interactions, your doctor should manage all of your medications carefully. Felodipine: Moderate Coadministration of felodipine and metoprolol can reduce angina and improve exercise tolerance.
Common use

Toprol Xl acts mostly blocking beta-adrenoreceptors of the heart and is used to treat hypertension, chest pain (angina), abnormal rhythms of the heart, to treat and prevent myocardial infarction. This medication influences autonomic nervous system which stipulates increased heart rate by blocking its receptors and thus reducing abnormally rapid heart rhythms. It also diminishes myocard irritability, cardiac output and causes other effects.



Dosage and direction

This medication should be taken with food or just after a meal. Do not chew, squash or break a tablet, drink a glass of water with it. Dosage depends on the treated disease and may vary between 100-450 mg daily. Your individual dosage should be prescribed by your physician. Aged patients are recommended to start from 50 mg daily dose. Kidney failure does not require a dosage correction while liver failure requires usage of other beta-adrenoblockers which are not destructed in liver.



Precautions

Avoid drinking alcohol as its interaction with Toprol Xl increases drowsiness and dizziness.



Contraindications

Hypersensitivity to the components of the medication, acute or chronic heart failure, arterial hypotention, congestive heart failure, asthma or other breathing problems, diabetes, disorders of peripheral blood circulation, pregnancy, breast-feeding, depression, liver or kidney disease, a thyroid disorder, or myasthenia gravis.



Possible side effect

At the background of common tolerance to the medication among side effects are noticed abdominal cramps, fatigue, insomnia, nausea, depression, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, diarrhea, constipation, and shortness of breath or wheezing.



Drug interaction

Attention should be paid to intake of calcium channel blockers and digoxin (Lanoxin) which are known by dangerous lowering of blood pressure and heart rate being administered together with Toprol Xl.

Toprol Xl also is able to mask the early symptoms of low blood sugar and should be used with caution in patients suffering from diabetes.



Missed dose

Take the forgotten dose when you remember. If your next dose is less than 4 hours away, skip it and return to your schedule. Do not try to compensate a missed dose by taking an extra one.



Overdose

In case such symptoms of Toprol Xl are noticed: uneven heartbeats, shortness of breath, dizziness, weakness or fainting, bluish-colored fingernails, seek for immediate medical help.



Storage

Store between 15-30 C (59-86 F). Protect this drug from moisture and dispensed in tight, keep in a light-resistant container.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Doxycycline

Active Ingredients:

  • Doxycycline

Action mechanism and therapeutic effect of the medication:

Doxycycline is half-synthetic tetracycline antibiotic with a broad spectrum of antibacterial activity. Doxycycline exerts bacteriostatic action associated with suppressing the synthesis of proteins on ribosomes in microbial cell. Doxycycline is active against aerobic gram-positive bacteria Staphylococcus spp, Bacillus anthracis, Listeria monocytogenes; aerobic bacteria:Clostridium spp.

Medical indications: Doxycycline is indicated for the treatment of infections caused by sysceptible microorganisms:

  • ENT infections
  • Gastrointestinal infections
  • Infections of the upper and lower respiratory system
  • Skin and soft tissue infections
  • Urogenital infections
  • Syphilis (when unable to take penicillin)
  • Some respiratory or urinary tract infections (UTIs)
  • Plague
  • Cholera
  • Certain types of pneumonia
  • Chlamydia
  • Rocky Mountain spotted fever
  • Tularemia
  • Typhus fever
  • Tick fever
  • Gonorrhea
  • Lyme disease
  • Anthrax infection treatment
  • Rosacea treatment
  • Gum disease treatment
  • Malaria treatment

Doxycyline contradictions, precautions and warnings:

Doxycycline is contraindicated for use in:

  • Hypersensitivity to doxycycline and other components of the medication
  • Severe liver diseases
  • Severe kidney diseases
  • History of pseudo-membranous colitis
  • Pregnancy (Doxycycline is a pregnancy category D meaning that it can cause significant damage to the fetus)
  • Breastfeeding
  • Frequent yeast infections

Doxycyline side effects:

As with any other drug, side effects can occur with Doxycyline. However, it does not mean that everyone who takes the medicine will experience these adverse effects. In most cases the preparation is well tolerated. The most common Doxycycline side effects include:

  • Decreased appetite
  • Vomiting
  • Stomach pain
  • Heartburn
  • Diarrhea
  • Photo-sensitivity
  • Nausea

If any side effects occur during the treatment make sure to consult your health care provider immediately. If you are unsure about anything related to Doxycyline, please talk to your doctor or pharmacist.

Drug interaction:

Doxycyline can potentially interact with the following groups of drugs:

  • Aluminum, calcium, magnesium, or iron products
  • Bile-acid sequestrant cholesterol drugs
  • Barbiturates
  • Peniccilins
  • Oral typhoid vaccine
  • Birth control pills
  • Anti-diarrheal drug (Bismuth subsalicylate)
  • Bipolar disorder treatment (Carbamazepine)
  • HIV treatment (Maraviroc)
  • Retinoids
  • Blood thinners (Warfarin)
  • ACE inhibitor (Quinapril)
  • Aldosterone antagonist (Eplerenone)
  • Opioid pain killer (Fentanyl)
  • Anticonvulsant (phenytoin)

It is possible that all drug interactions are not presented above. For this reason, we recommend you to talk with your health care provide about drug interactions with Doxycyline which may apply to you.

Additional information for the patients:

The preparation should be taken according to your doctor's recommendations. Never take the drug for conditions which are not presented in the the drug's leaflet. Try to keep the medicine out of the reach of children.